Publications @ SKKU

2026

14.

Preorganization-driven site-selective N-functionalization of dual nucleophilic amino alcohols in basic aqueous media

Geun Ho Kim, Yeonju Lee, Kwangmin Shin, and Jung Woon Yang*

Organic Chemistry Frontiers 2026, 13, 5568-5577.

13.

HFIP-Promoted PdH-Electrocatalytic Remote Ritter-Type Hydrofunctionalization of Alkenes: Divergent Access to Amides and Tetrazoles

Seungdae Park, Taehwan Kim, Junhyeon Choi, Do Hyun Ryu, and Kwangmin Shin*

Organic Letters 2026, 28, 5580-5585.

Highlighted in OPR&D

12.

L-Proline-Derived Chiral Primary Amine/Copper Dual Catalysis: Highly Chemo- and Enantioselective α-Amination Reactions of Branched β-Ketocarbonyls

Jiwan Yun, Sudip Shit, Jin Won Lee, Kyongchan Kwon, Kwangmin Shin, and Do Hyun Ryu*

Organic Letters 2026, 28, 229-235.

2025

11.

Modular Access to Quaternary α‑Cyano Carbonyl Compounds via NiH Catalysis

Yoonho Lee, Yujin Jung, Seonhwa Choo, and Kwangmin Shin*

JACS Au 2025, 5, 4506-4158.

10.

Synthesis of α-Aryl Ketones via the Nickel-Catalyzed Hydroacylation of Aryl Alkenes with Aroyl Fluorides

Yoonho Lee†, Yujin Jung†, Seonhwa Choo, and Kwangmin Shin*

(† These authors contributed equally to this work.)

Organic Syntheses 2025, 102, 367-380.

Invited article

09.

PdH-Electrocatalytic Formal Conjugate Fluorination of β-Aryl-α,β-Unsaturated Amides with Mild and Safe Nucleophilic Fluorine Source s

Baeho Yang†, Dohyun Lee†, and Kwangmin Shin*

(† These authors contributed equally to this work.)

The Journal of Organic Chemistry 2025, 90, 10058-10063.

2024

08.

Electrooxidative Pd-Catalyzed Remote Hydrofunctionalization of Alkenes with Nucleophiles

Seungdae Park, Baeho Yang, Dohyun Lee, Hyunwoo Kim*, and Kwangmin Shin*

ACS Catalysis 2024, 14, 15858-15868.

2023

05.

Electrocatalytic Access to Azetidines via Intramolecular Allylic Hydroamination: Scrutinizing Key Oxidation Steps through Electrochemical Kinetic Analysis

Steve H. Park, Geunsu Bae, Ahhyeon Choi, Suyeon Shin, Kwangmin Shin*, Chang Hyuck Choi*, and Hyunwoo Kim*

Journal of the American Chemical Society 2023, 145, 15360-15369.

Highlighted in OPR&D

04.

Palladium-Catalyzed Electrooxidative Hydrofluorination of Aryl-Substituted Alkenes with Nucleophilic Fluorine Source

Anup Mandal, Jieun Jang, Baeho Yang, Hyunwoo Kim*, and Kwangmin Shin*

Organic Letters 2023, 25, 195-199.

Highlighted in Organic Chemistry Portal

2022

03.

Copper Hydride-Catalyzed Enantioselective Olefin Hydro-methylation

Yuyang Dong, Kwangmin Shin, Binh Khanh Mai, Peng Liu*, and Stephen L. Buchwald*

Journal of the American Chemical Society 2022, 144, 16303-16309.

02.

Ligand-Free NiH-Catalyzed Hydroacylation of Aryl Alkenes with Aroyl Fluorides

Jihye Kim†, Jieun Jang†, Yoonho Lee, and Kwangmin Shin*

(† These authors contributed equally to this work.)

Organic Letters 2022, 24, 5412-5416.

Highlighted in Organic Chemistry Portal

01.

Electrocatalytic Radical-Polar Crossover Hydroetherification of Alkenes with Phenols

Steve H. Park, Jieun Jang, Kwangmin Shin*, and Hyunwoo Kim*

ACS Catalysis 2022, 12, 10572-10580.

Prior to Independent Career

16. Li, C.†; Shin, K.†; Liu, R. Y.; Buchwald, S. L.* Engaging Aldehydes in CuH-Catalyzed Reductive Coupling Reactions: Stereoselective Allylation with Unactivated 1,3-Diene Pronucleophiles. Angew. Chem., Int. Ed. 2019, 58, 17074-17080. († These authors contributed equally to this work.)

15. Kim, J. †; Shin, K. †; Jin, S.; Kim, D.; Chang, S.* Oxidatively Induced Reductive Elimination: Exploring the Scope and Catalyst Systems with Ir, Rh, and Ru Complexes. J. Am. Chem. Soc. 2019, 141, 4137-4146. († These authors contributed equally to this work.)

14. Shin, K.; Park, Y.; Baik, M.-H.; Chang, S. Iridium-Catalysed Arylation of C-H Bonds Enabled by Oxidatively Induced Reductive Elimination. Nat. Chem. 2018, 10, 218-224.

13. Shin, K.†; Joung, S.†; Kim, Y.; Chang, S.* Selective Synthesis of Silacycles by Borane-Catalyzed Domino-Hydrosilylation of Proximal Unsaturated Bonds: Tunable Approach to 1,n-Diols. Adv. Synth. Catal. 2017, 359, 3428-3436. († These authors contributed equally to this work.)

12. Shin, K.; Park, S.-W.; Chang, S.* Cp*Ir(III)-Catalyzed Mild and Broad C-H Arylation of Arenes and Alkenes with Aryldiazonium Salts Leading to the External Oxidant-Free Approach. J. Am. Chem. Soc. 2015, 137, 8584-8592.

11. Kim, J.; Shin, K.; Chang, S.* Rh(III)-and Ir(III)-Catalyzed Direct C-H Bond Transformations to Carbon-Heteroatom Bonds. Top. Organomet. Chem. 2015, 55, 29-51.

10. Shin, K.; Kim, H.; Chang, S.* Transition Metal-Catalyzed C-N Bond Forming Reactions Using Organic Azides as the Nitrogen Source: A Journey for the Mild and Versatile C-H Amination. Acc. Chem. Res. 2015, 48, 1040-1052.

9. Shin, K.; Chang, S.* Iridium(III)-Catalyzed Direct C-7 Amination of Indolines with Organic Azides. J. Org. Chem. 2014, 79, 12197-12204.

8. Kim, H.; Shin, K.; Chang, S.* Iridium-Catalyzed C-H Amination with Anilines at Room Temperature: Compatibility of Iridacycles with External Oxidants. J. Am. Chem. Soc. 2014, 136, 5904-5907.

7. Li, B.; Lee, S.; Shin, K.; Chang, S.* Chelation-Assisted Hydroesterification of Alkenes: New Ruthenium Catalyst Systems and Ligand Effects. Org. Lett. 2014, 16, 2010-2013.

6. Shin, K.; Ryu, J.; Chang, S.* Orthogonal Reactivity of Acyl Azides in C-H Activation: Dichotomy Between C-C and C-N Amidations Based on Catalyst Systems. Org. Lett. 2014, 16, 2022-2025.

5. Park, S. H.; Kwak, J.; Shin, K.; Ryu, J.; Park, Y.; Chang, S.* Mechanistic Studies of the Rhodium-Catalyzed Direct C-H Amination Reaction Using Azides as the Nitrogen Source. J. Am. Chem. Soc. 2014, 136, 2492-2502.

4. Ryu, J.; Kwak, J.; Shin, K.; Lee, D.; Chang, S.* Ir(III)-Catalyzed Mild C-H Amidation of Arenes and Alkenes: An Efficient Usage of Acyl Azides as the Nitrogen Source. J. Am. Chem. Soc. 2013, 135, 12861-12868.

3. Shin, K.; Baek, Y.; Chang, S.* Direct C-H Amination of Arenes with Alkyl Azides under Rhodium Catalysis. Angew. Chem., Int. Ed. 2013, 52, 8031-8036.

2. Ryu, J.; Shin, K.; Park, S. H.; Kim, J. Y.; Chang, S.* Rhodium-Catalyzed Direct C-H Amination of Benzamides with Aryl Azides: A Synthetic Route to Diarylamines. Angew. Chem., Int. Ed. 2012, 51, 9904-9908.

1. Kim, J.; Choi, J.; Shin, K.; Chang, S.* Copper-Mediated Sequential Cyanation of Aryl C-B and Arene C-H Bonds Using Ammonium Iodide and DMF. J. Am. Chem. Soc. 2012, 134, 2528-2531.

Publications @ SKKU

2026

2025

2024

2023

2022

Prior to Independent Career

16. Li, C.†; Shin, K.†; Liu, R. Y.; Buchwald, S. L.* Engaging Aldehydes in CuH-Catalyzed Reductive Coupling Reactions: Stereoselective Allylation with Unactivated 1,3-Diene Pronucleophiles. Angew. Chem., Int. Ed. 2019, 58, 17074-17080. († These authors contributed equally to this work.)

15. Kim, J. †; Shin, K. †; Jin, S.; Kim, D.; Chang, S.* Oxidatively Induced Reductive Elimination: Exploring the Scope and Catalyst Systems with Ir, Rh, and Ru Complexes. J. Am. Chem. Soc. 2019, 141, 4137-4146. († These authors contributed equally to this work.)

14. Shin, K.; Park, Y.; Baik, M.-H.*; Chang, S.* Iridium-Catalysed Arylation of C-H Bonds Enabled by Oxidatively Induced Reductive Elimination. Nat. Chem. 2018, 10, 218-224.

13. Shin, K.†; Joung, S.†; Kim, Y.; Chang, S.* Selective Synthesis of Silacycles by Borane-Catalyzed Domino-Hydrosilylation of Proximal Unsaturated Bonds: Tunable Approach to 1,n-Diols. Adv. Synth. Catal. 2017, 359, 3428-3436. († These authors contributed equally to this work.)

12. Shin, K.; Park, S.-W.; Chang, S.* Cp*Ir(III)-Catalyzed Mild and Broad C-H Arylation of Arenes and Alkenes with Aryldiazonium Salts Leading to the External Oxidant-Free Approach. J. Am. Chem. Soc. 2015, 137, 8584-8592.

11. Kim, J.; Shin, K.; Chang, S.* Rh(III)-and Ir(III)-Catalyzed Direct C-H Bond Transformations to Carbon-Heteroatom Bonds. Top. Organomet. Chem. 2015, 55, 29-51.

10. Shin, K.; Kim, H.; Chang, S.* Transition Metal-Catalyzed C-N Bond Forming Reactions Using Organic Azides as the Nitrogen Source: A Journey for the Mild and Versatile C-H Amination. Acc. Chem. Res. 2015, 48, 1040-1052.

9. Shin, K.; Chang, S.* Iridium(III)-Catalyzed Direct C-7 Amination of Indolines with Organic Azides. J. Org. Chem. 2014, 79, 12197-12204.

8. Kim, H.; Shin, K.; Chang, S.* Iridium-Catalyzed C-H Amination with Anilines at Room Temperature: Compatibility of Iridacycles with External Oxidants. J. Am. Chem. Soc. 2014, 136, 5904-5907.

7. Li, B.; Lee, S.; Shin, K.; Chang, S.* Chelation-Assisted Hydroesterification of Alkenes: New Ruthenium Catalyst Systems and Ligand Effects. Org. Lett. 2014, 16, 2010-2013.

6. Shin, K.; Ryu, J.; Chang, S.* Orthogonal Reactivity of Acyl Azides in C-H Activation: Dichotomy Between C-C and C-N Amidations Based on Catalyst Systems. Org. Lett. 2014, 16, 2022-2025.

5. Park, S. H.; Kwak, J.; Shin, K.; Ryu, J.; Park, Y.; Chang, S.* Mechanistic Studies of the Rhodium-Catalyzed Direct C-H Amination Reaction Using Azides as the Nitrogen Source. J. Am. Chem. Soc. 2014, 136, 2492-2502.

4. Ryu, J.; Kwak, J.; Shin, K.; Lee, D.; Chang, S.* Ir(III)-Catalyzed Mild C-H Amidation of Arenes and Alkenes: An Efficient Usage of Acyl Azides as the Nitrogen Source. J. Am. Chem. Soc. 2013, 135, 12861-12868.

3. Shin, K.; Baek, Y.; Chang, S.* Direct C-H Amination of Arenes with Alkyl Azides under Rhodium Catalysis. Angew. Chem., Int. Ed. 2013, 52, 8031-8036.

2. Ryu, J.; Shin, K.; Park, S. H.; Kim, J. Y.; Chang, S.* Rhodium-Catalyzed Direct C-H Amination of Benzamides with Aryl Azides: A Synthetic Route to Diarylamines. Angew. Chem., Int. Ed. 2012, 51, 9904-9908.

1. Kim, J.; Choi, J.; Shin, K.; Chang, S.* Copper-Mediated Sequential Cyanation of Aryl C-B and Arene C-H Bonds Using Ammonium Iodide and DMF. J. Am. Chem. Soc. 2012, 134, 2528-2531.

14. Shin, K.; Park, Y.; Baik, M.-H.; Chang, S. Iridium-Catalysed Arylation of C-H Bonds Enabled by Oxidatively Induced Reductive Elimination. Nat. Chem. 2018, 10, 218-224.